The way the game works is simple; the casino does have an edge, but on a particular short term streak a player could get very lucky and end up winning a very large amount of money. The best way in which to try and get yourself to a point where you can do that is to learn the optimal strategy of Caribbean Poker. It is impossible obviously to control luck, but you can make sure that you make the correct mathematical play 100% of the time and reduce the house edge to as small as it is likely to get.
The way to do this, quite simply, is to play any hand that is better than AK high. AK high is the minimum hand that the dealer has to qualify on and therefore ensuring that your hands are always at least one hand better than that is definitely the way to go. This takes into account not only your likelihood of winning, but also the fact that when you fold before seeing a showdown you end up losing the ante bet you just made. As a hand, a pair of twos is likely to lose a lot of the time, but at the same time folding a pair of twos will force you to lose 100% of the time. This is why it is a good idea from an optimal strategy point of view to play the game with a wide selection of starting hands.
As for the progressive jackpot, there are two ways of looking at it. The first way resides in the idea of reducing the house edge as much as possible and if you want to reduce the house edge as much as possible then you are going to try and play the progressive jackpot as little as possible. You would need some really high odds, in the region of something like 30,000 to 1, in order to make playing the progressive jackpot worthwhile. However, the progressive jackpot, even if it is not at those odds levels, is still extremely large and therefore you will feel a lot of remorse if you hit a lucky streak and fail to take advantage of it through the playing of the progressive jackpot. There is also the idea that you are there to have fun and there is nothing more fun than hoping you win the jackpot! The choice is ultimately up to you, but those are the two logical lines of thinking that people have concerning the progressive jackpot.